Open Access Highly Accessed Open Badges Brief report

Treatment of refractory uveitic macular edema with dexamethasone intravitreal implants in a pediatric patient with bilateral granulomatous idiopathic panuveitis: a case report

Serge Bourgault12*, Maryam Aroichane3, Leah A Wittenberg1, Andréane Lavallée12 and Patrick E Ma1

Author Affiliations

1 Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, British Columbia V5Z 3N9, Canada

2 Département d’Ophtalmologie et ORL - Chirurgie cervico-faciale, Université Laval, Québec, Québec G1V 0A6, Canada

3 Department of Ophthalmology and Visual Sciences, British Columbia Children’s Hospital, University of British Columbia, Vancouver, British Columbia V6H 3N1, Canada

For all author emails, please log on.

Journal of Ophthalmic Inflammation and Infection 2013, 3:61  doi:10.1186/1869-5760-3-61

Published: 22 October 2013



Macular edema is a common complication of uveitis and represents a therapeutic challenge, especially in children. Recently, intravitreal dexamethasone implants have been shown to decrease intraocular inflammation and to control uveitic macular edema in patients with non-infectious intermediate or posterior uveitis.


An 11-year-old boy with bilateral granulomatous idiopathic panuveitis and orbital inflammation experienced macular edema refractory to topical steroids and subcutaneous methotrexate. He was treated with off-label bilateral injections of dexamethasone intravitreal implant. Three months later, his vision had improved from 20/200 in both eyes to 20/30 in the right eye and 20/40 in the left eye. Optical coherence tomography showed complete resolution of the cystoid macular edema and subretinal fluid in both eyes.


This is a rare report of the use of bilateral dexamethasone intravitreal implant in a pediatric patient. The implants achieved complete resolution of the uveitic macular edema with no adverse events 3 months post-implantation.

Dexamethasone intravitreal implant; Ozurdex®; Cystoid macular edema; Uveitic macular edema; Uveitis; Panuveitis; Pediatric uveitis